A Perth-based company has developed a plant-based anti-inflammatory pill that significantly reduces period pain and premenstrual symptoms, according to a study published in the International Journal of Women’s Health.
The supplement, called Khapregesic, is made from the bark of Khaya senegalensis, or African mahogany, traditionally used in herbal medicine for menstrual cramps and PMS. The randomized, double-blind, placebo-controlled trial involving 84 women found that Khapregesic reduced pain by 136% compared to placebo and improved mood swings and mild anxiety by nearly 200%.
Perth teacher Daisy McCulloch, who has polycystic ovary syndrome and stage three endometriosis, reported significant relief after using the product. “My cramps, nausea, and inflammation have eased from severe to mild-to-moderate,” she said.
Hey Sister! co-founder Rick Ferdinands noted that the study also assessed long-term safety, with participants taking three times the recommended dose daily for 28 days. The company plans to amend its Therapeutic Goods Administration listing to reflect safety data and is finalizing a US Food and Drug Administration application.
The findings pave the way for further research on long-term efficacy, with Ferdinands stating, “We’re working on our next strategy of doing it over three months and maybe even 12 months.”
