Victoria's Department of Health has issued an urgent alert after the powerful anaesthetic etomidate was detected in a vape product sold in Melbourne, resulting in one person being hospitalised. The discovery has raised fears that the dangerous substance may be more widespread in illicit vapes across Australia.
What is Etomidate?
Etomidate is a potent, rapid-onset sedative used medically for anaesthesia. Its effects can include confusion, vomiting, ineffective breathing, and loss of consciousness. The Department of Health warned that these effects may be life-threatening, especially when combined with alcohol, opioids, benzodiazepines, GHB/1,4 BD/GBL, or other sedatives. Repeated exposure can also disrupt the body's stress hormone system, leading to weakness, dizziness, confusion, and collapse.
Incident in Melbourne
Authorities have not disclosed the exact location in Melbourne where the tainted vape was purchased, but the person who inhaled it required hospital treatment. The department urged the public to be vigilant, noting that illicit vapes sold under names such as space oil, k-pods, or space vapes may contain etomidate or other harmful substances.
Signs of Toxicity and Response
Reduced consciousness is the primary sign of serious sedative toxicity. In some cases, the person may also have difficulty or laboured breathing. While naloxone can reverse opioid overdoses, it does not counteract the effects of etomidate. Health officials advise seeking immediate medical help if someone shows signs of severe sedation after vaping.
International Context
This is not an isolated case. In late 2025, several people in New Zealand were hospitalised after using illegal vapes containing etomidate. Singapore has also cracked down on etomidate-laced vapes, imposing heavier fines and longer prison sentences, despite a nationwide ban on vapes and e-cigarettes since 2018. Singapore's Prime Minister Lawrence Wong warned in August 2025: "The vapes themselves are just delivery devices. The real danger is what's inside. Right now, it's etomidate. In future, it could be something worse, stronger, far more dangerous drugs."
Ongoing Concerns
The Victorian Department of Health continues to monitor the situation and urges anyone who experiences severe symptoms after using vapes to seek emergency care. The incident highlights the risks of unregulated vaping products and the potential for hidden, dangerous ingredients.
